European Radiology

ISSN: 0938-7994 (printed version)
ISSN: 1432-1084 (electronic version)
DOI: 90091882.330

Volume 9 Issue 9 (1999) pp 1882-1885

Publication Date 11/23/1999 (printed version)

Diagnosis of neonatal hemochromatosis with MR imaging and duplex Doppler sonography

Springer-Verlag; LINK PDF Full Text


Abstract. Neonatal hemochromatosis is a rare congenital disorder which affects both fetuses and newborns. It is characterized by hepatocellular failure, often appearing on the first day of life in the form of coagulopathy, hypoalbuminemia, hypoglycemia, and jaundice. Most of the affected infants die early in life, and definitive diagnosis has often been made only by post-mortem evaluation. With the help of MRI, plus increasing awareness of the disorder, diagnosis is now often made early, even in utero. Duplex Doppler sonography does not provide information on siderosis but shows abnormalities in the liver or blood-flow patterns associated with liver disease.


M. Oddone ; C. Bellini ; W. Bonacci ; M. Bartocci ; P. Toma ; G. Serra

Key words: Neonatal liver failure Neonatal hemochromatosis Newborn MRI Duplex Doppler sonography