COMPARATIVE
NUTRITION OF IRON AND COPPERAnnu. Rev. Nutr. 1997 Joy J. Winzerling and John H. Law
Departments of Biochemistry, Entomology, and Nutritional Sciences and the Center
for Insect Science, University of Arizona, Tucson, Arizona 85721
DMT1 gene expression and cadmium absorption in human absorptive enterocytes.
Toxicol Lett. 2001 Jun 20 Divalent metal transporter
1 (DMT1) is a transmembrane, proton-coupled metal ion transporter that is
upregulated in the duodenum of iron-deficient rodents and in hereditary
hemochromatosis patients, suggesting that it may constitute a key factor in the
uptake of dietary iron. In summary, our results indicate that the uptake
of cadmium into human absorptive enterocytes may be mediated by DMT1.
Increased
cerebral iron uptake in Wilson's disease: a 52Fe-citrate PET study. J Nucl Med 2000 May Toxicity of abundant copper is the main cause of brain
and liver tissue damage in patients with Wilson's disease (WD). However, there
is also evidence of a disturbed iron metabolism in this genetically determined
disorder.
Zellweger Syndrome Information Page
National Institute of Neurological Disorders and Stroke The most
common features of Zellweger syndrome include an enlarged liver, high levels of
iron and copper in the blood, and vision disturbances.