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HEMATOLOGIC VALUES

SERUM FERRITIN, IRON, TOTAL IRON-BINDING CAPACITY AND TRANSFERRIN SATURATION
Appendix 43.
Test Name Age   Male Subjects Female Subjects
 
Ferritin ng/ml ΅g/l ng/ml ΅g/l
  1- 30 days † 6 - 400 6 - 400 6 - 515 6 - 515
1- 6 months † 6 - 410 6 - 410 6 - 340 6 - 340
7 - 12 months † 6 - 80 6 - 80 6 - 45 6 - 45
1- 5 years * ‡ 6 - 24 6 - 24 6 - 24 6 - 24
6 - 9 years * ‡ 10 - 55 10 - 55 10 - 55 10 - 55
10 - 14 years ‡ 23 - 70 23 - 70 6 - 40 6 - 40
14 - 19 years ‡ 23 - 70 23 - 70 6 - 40 6 - 40
 
Iron ΅g/dl ΅mol/L ΅g/dl ΅mol/L
  1- 5 years * ‡ 22 - 136 4 - 25 22 - 136 4 - 25
6 - 9 years * ‡ 39 - 136 7 - 25 39 - 136 7 - 25
10 - 14 years ‡ 28 - 134 5 - 24 45 - 145 8 - 26
14 - 19 years ‡ 34 - 162 6 - 29 28 - 184 5 - 33
 
Iron-Binding Capacity  
  1- 5 years * ‡ 268 - 441 48 - 79 268 - 441 48 - 79
6 - 9 years * ‡ 240 - 508 43 - 91 240 - 508 43 - 91
10 - 14 years ‡ 302 - 508 54 - 91 318 - 575 57 - 103
14 - 19 years ‡ 290 - 570 52 - 102 302 - 564 52 - 101
 
Transferrin Saturation  
  1- 5 years * ‡ 0.07 - 0.44 0.07 - 0.44
6 - 9 years * ‡ 0.17 - 0.42 0.17 - 0.42
10 - 14 years ‡ 0.11 - 0.36 0.02 - 0.40
14 - 19 years ‡ 0.06 - 0.33 0.06 - 0.33
 
Transferrin U/L (males and females)
  0 - 5 days §   1.43 - 4.46  
1 - 3 years §   2.18 - 3.47  
4 - 6 years §   2.08 - 3.78  
7 - 9 years §   2.25 - 3.61  
10 - 13 years §   2.24 - 4.42  
14 - 19 years §   2.33 - 4.44  
* No significant differences between males and females; range derived from combined data.
† Saldin SJ, Morales A, et al: Pediatric reference ranges on the Abbott MX for FSH, LH, prolactin, TSH, T4, T3, free T3, T-uptake, lgE and ferritin. Clin Biochem 1995; 28; 603. Study based on hospitalized patients, values represent 2.5 and 97.5th percentiles.
‡ Lockitch G, Halstead AC, et al: Age- and sex-specific pediatric reference intervals for zinc, copper, selenium, iron, vitamins A and E and related proteins. Clin Chem 1998; 34:1625, Study based on healthy children values represent the 0.025 and 0.975 fractiles. Transferrin saturation calculated from iron (΅mol/L)/TIBC. Note that the lower reference limits for serum iron and transferrin saturation in this study are below the limits used to define acceptable levels for these two analytes. (See O’Neal RM, Johnson OC, and Schaefer AE: Guidelines for the classification and interpretation of group blood and urine data collected as part of the National Nutritional Survey. Pediatr Res 1970; 4; 103).
§ Lockitch G, Halstead AC, et al: Age- and sex-specific pediatric reference intervals: study design and methods illustrated by measurement of serum proteins with the Behring LN nephelometer. Clin Chem 1998; 34; 1618. Results are 2.5-97.5 percentiles.
Source: Nathan & Oskis Hematology of Infancy & Chilhood, 5th Edition, Vol. 2, copyrighted 73, 81, 87, 93, 98 edited by David G. Nathan & Stuart H. Orkin, of Harvard Medical School

Last Updated on 5/18/99